Lymphomatoid Granulomatosis as a Debut of Common Variable Immunodeficiency: A Case Report and Review of Literature

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Author(s) 

Magdalena Fernández-García^1*, Tetyana Zhuravetska², Jose Luis Rodríguez³, Elsa Ots²

Affiliation(s)

¹Department of Internal Medicine, Hospital Marqués de Valdecilla-IDIVAL, University of Cantabria, RETICEF, Santander, Spain.
²Department of Intensive Care, Hospital Marqués de Valdecilla, Santander, Spain.
³Department of Anatomic Pathology, Hospital Marqués de Valdecilla, Santander, Spain.

ABSTRACT

Lymphomatoid granulomatosis, currently called as extranodal angiocentric and angiodestructive immunoproliferative disorder, is a rare entity of unclear etiology. It involves most frequently lungs, central nervous system and skin. The clinical course is variable, but mortality is high. Today, it represents a diagnostic challenge because it can emulate autoimmunity, infection, and malignancy processes. Optimal therapy scheme is still unknown. We report the case of a 20 year-old man presenting with fever, weight loss, sweating, multiple bilateral lung nodules on the chest X-ray and cutaneous involvement.

KEYWORDS

Lymphomatoid Granulomatosis, Common Variable Immunodeficiency, Epstein-Barr Virus

Cite this paper

Fernández-García, M. , Zhuravetska, T. , Rodríguez, J. and Ots, E. (2014) Lymphomatoid Granulomatosis as a Debut of Common Variable Immunodeficiency: A Case Report and Review of Literature. Journal of Biosciences and Medicines, 2, 13-15. doi: 10.4236/jbm.2014.28002. 

 

References

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