The Protective Effect of Grape Seed Extract on Cardiotoxicity Induced by Doxorubicin Drug in Male Rats
Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52565#.VJt07cCAM4 Author(s) Noorah Saleh Al-Sowayan , Nadia H. Mahmoud Affiliation(s) Department of Biology, Faculty of Science, Qassim University, Buraydah, Saudi Arabia . ABSTRACT Objective: This work was designed to determine the productive effect of grape seed proanthocynadine extract (GSPE) and Vitamin E against Doxorubicin (DOX) induced myocardial toxicity in 50 male. Wister rates were divided in five groups. The 1 st group was untreated and served as a control. The 2 nd group was treated with DOX only, the 3 rd group was pretreated with GSPE, the 4 th group was pretreated with Vitamin E, and the 5 th group was pretreat...