跳至主要内容

Pregnancy with Gastric Stromal Tumor

Gastrointestinal stromal tumors (GIST) are rare tumors of the GI tract and account for less than 1% of gastrointestinal tumors, but they are the most common mesenchymal neoplasms of the gastrointestinal tract. They are usually found in the stomach or small intestine, but can occur anywhere along the gastrointestinal (GI) tract and may rarely have extra-GI involvement. Its early diagnosis is important for preserving the prognosis. Microscopy and immunohistochemistry allowed classifying these tumors according to their phenotypes and prognosis. The two main markers identified were CD34, and KIT protein or CD 117.

In this paper, the authors reported a case of a patient who was admitted in our university hospital for GIST discovered during the second trimester of pregnancy. She was 42 years old, in the fifth months of pregnancy. She was admitted for biliary colic pain with vomiting. On abdominal examination, they objectified a distended abdomen with uterine height of 18 cm and epigastric mass of 10 cm. Abdominal ultrasound and magnetic resonance imaging (MRI) showed a hepatic, tissue and cystic mass, developing at the expense of the left liver. Endoscopy objectified an aspect of extrinsic compression at the front of the stomach. A cesarean was scheduled at the 35th month of pregnancy for fetal extraction and rescue. Exploration of the peritoneal cavity during surgery had objectified a hepatic highly vascularised mass reaching up to the umbilicus. This mass was unresectable. A postoperative CT scan revealed a large bilobed epigastric mass adhering to the stomach and the left liver. Histological and immunohisto- chemical study of hepatic process showed a gastrointestinal stromal tumor of high risk of malignancy. Then multidisciplinary management was carried out, which had better managed the mother and her baby.

In summary, gastrointestinal stromal tumors during pregnancy are extremely rare. It is very important to discuss their diagnosis and treatment in multidisciplinary meeting and it is also very important to know their prognostic factors and treatment options.

Article by Iliass Charif, et al, from Sidi Mohammed Ben Abdellah University, Fez, Morocco.

Full access: http://mrw.so/qKS3Q 

Image by Mary Zen, from Flickr-cc.

评论

发表评论

此博客中的热门博文

Identifying Sustainable Practices for Tapping and Sap Collection from Birch Trees

Tapping and collecting sap from birch trees ( Betula , sp.) for the production of beverages and syrup is gaining increased levels of interest. Although the practice of tapping birch trees and collecting sap has been ongoing for millennia across the world, there remain some critical data needed in order to make science-based decisions about the production practices required to optimize yields and ensure sustainable outcomes are achieved in the long-term. In this study, experiments were conducted to determine two pieces of information essential to identify practices necessary to ensure tapping trees for birch sap collection were both sustainable and profitable—the selection of the time to initiate tapping birch trees to obtain maximum yields, and the volume of nonconductive wood (NCW) associated with taphole wounds in birch trees. The yields obtained from various timing treatments varied between sapflow seasons, but indicated that using test tapholes to choose the appropriate ti
发表评论
阅读全文

Incorporation of High-Altitude Balloon Experiment in High School Science Classrooms

High-altitude balloon is a balloon, filled usually with helium or hydrogen that ascends into an area called “near space” or stratosphere. The most common type of high-altitude balloons are weather balloons. Other purposes include use as a platform for experiments in the upper atmosphere. Modern balloons generally contain electronic equipment such as radio transmitters, cameras, or satellite navigation systems, such as GPS receivers. The mission of the High-Altitude Balloon Experiment (HABE) is to acquire supporting data, validate enabling technologies, and resolve critical acquisition, tracking, and pointing (ATP) and fire control issues in support of future space-based precision pointing experiments. The use of high-altitude balloons offers a relatively low-cost, low-vibration test platform, a recoverable and reusable payload, worldwide launch capability, and a 'near- space' emulation of the future space systems operational scenarios. More recently, several university
1 条评论
阅读全文

Esophageal Carcinogenesis

Read full paper at: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50380#.VDy9v1fHRK0 Author(s)   Naoki Watanabe 1 , Masahito Shimizu 2 , Takahiro Kochi 2 , Yohei Shirakami 2 , Takuji Tanaka 1,3* Affiliation(s) 1 Department of Diagnostic Pathology (DDP) & Research Center of Diagnostic Pathology (RC-DiP), Gifu Municipal Hospital, Gifu, Japan . 2 Department of Internal Medicine/Gastroenterology, Gifu University Graduate School of Medicine, Gifu, Japan . 3 Department of Tumor Pathology, Gifu University Graduate School of Medicine, Gifu, Japan . ABSTRACT Esophageal cancer is the sixth leading cause of cancer death and remains one of the least survivable cancers. Esophageal cancers show wide variations in incidence in different pop
发表评论
阅读全文