Diversity of Secondary Metabolites from Two Antarctic Microbes Rhodococcus sp. NJ-008 and Pseudomonas sp. NJ-011
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Author(s)
Key
Laboratory of East China Sea & Oceanic Fishery Resources
Exploitation and Utilization, Ministry of Agriculture, East China Sea
Fisheries Research Institute, Chinese Academy of Fishery Sciences,
Shanghai, China; Shanghai Ocean University, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, China.
Diversity analysis on
secondary metabolites of Antarctic microbes, Rhodococcus sp. NJ-008 and Pseudomonas sp. NJ-011, together with the structural elucidation of some purified compounds,
has been carried out for understanding of their chemical constituents. The
methanol extracts of Rhodococcus sp.
NJ-008 and Pseudomonas sp. NJ-011 were
subjected to HPLC-TOF MS test for diversity analysis on secondary metabolites,
respectively. The chemical constituents of NJ-011 are mainly N-containing
compounds including some alkaloids and short polypeptides, while those of
NJ-008 are not N-containing ones. Three compounds were also isolated and
identified from extract of NJ011 by different column chromatography and
preparative HPLC, and their structures were elucidated as b-carboline (1),
3-benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione (2) and 3-isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
(3) by comparison of TOF MS, 1Hand 13C-NMR data with
those reported. More microbial material of Pseudomonas sp. NJ-011 should be needed for exploration of the minor constituents with
complicated structures.
Cite this paper
Wang, C. , Tian, X. , Yang, Q. , Lu, Y. , Ma, L. ,
Huang, H. and Fan, C. (2014) Diversity of Secondary Metabolites from
Two Antarctic Microbes Rhodococcus sp. NJ-008 and Pseudomonas sp. NJ-011. Open Journal of Marine Science, 4, 214-220. doi: 10.4236/ojms.2014.43020.
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